Benzodiazepines, particularly alprazolam, have been shown to be effective in the acute treatment of panic disorders. Difficult withdrawl and high relapse rates after successful discontinuation continue to be problems with this class of medication. Recent studies instituting cognitive-behavioral therapy as a treatment supplement to alprazolam taper have shown promising results out to one year follow-up. The present study investigated whether that combined treatment results in long-term improvement.
Bond '95, Steven M., "Long-Term Effectiveness of Combined Alprazolam and Cognitive-Behavioral Therapies in Panic Disorder" (1995). Honors Projects. Paper 112.