Event Title

Bismuth(III) bromide catalyzed 1,4-addition of indoles to chalcones

Faculty Advisor

Ram Mohan

Graduation Year

2020

Location

Center for Natural Sciences, Illinois Wesleyan University

Start Date

13-4-2019 9:00 AM

End Date

13-4-2019 10:00 AM

Description

Substituted indoles are of interest from a medicinal chemistry perspective. We have studied the utility of bismuth(III) bromide and other Lewis acid catalysts for the Michael addition of indoles to a variety of chalcones to yield substituted indoles. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.

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Apr 13th, 9:00 AM Apr 13th, 10:00 AM

Bismuth(III) bromide catalyzed 1,4-addition of indoles to chalcones

Center for Natural Sciences, Illinois Wesleyan University

Substituted indoles are of interest from a medicinal chemistry perspective. We have studied the utility of bismuth(III) bromide and other Lewis acid catalysts for the Michael addition of indoles to a variety of chalcones to yield substituted indoles. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.