Event Title

The Effect of Spinal Cord Stimulation for Chronic Pain Treatment

Faculty Advisor

Joe Williams

Graduation Year

2019

Location

Center for Natural Sciences, Illinois Wesleyan University

Start Date

13-4-2019 2:00 PM

End Date

13-4-2019 3:00 PM

Description

Spinal Cord Stimulation (SCS) is a form of therapy to treat forms of chronic pain. Although the efficacy of SCS treatment is relatively positive and is used clinically, the neurobiological mechanisms behind this treatment are not fully understood. The present study uses an animal model of chronic pain, involving transection of the sciatic nerve of one paw, to measure whether there are changes in the expression of following injury and subsequent SCS treatment. The study also examines the efficacy of different forms of SCS treatment by changing stimulation parameters (cathodic, anodic, symmetrical and asymmetrical stimulation parameters) and examines whether the degree of pain relief exhibited with each treatment correlates with changes in gene expression.

This document is currently not available here.

Share

COinS
 
Apr 13th, 2:00 PM Apr 13th, 3:00 PM

The Effect of Spinal Cord Stimulation for Chronic Pain Treatment

Center for Natural Sciences, Illinois Wesleyan University

Spinal Cord Stimulation (SCS) is a form of therapy to treat forms of chronic pain. Although the efficacy of SCS treatment is relatively positive and is used clinically, the neurobiological mechanisms behind this treatment are not fully understood. The present study uses an animal model of chronic pain, involving transection of the sciatic nerve of one paw, to measure whether there are changes in the expression of following injury and subsequent SCS treatment. The study also examines the efficacy of different forms of SCS treatment by changing stimulation parameters (cathodic, anodic, symmetrical and asymmetrical stimulation parameters) and examines whether the degree of pain relief exhibited with each treatment correlates with changes in gene expression.