A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

Authors

Ram Mohan, Illinois Wesleyan UniversityFollow
Matthew Bockman
Veronica Angeles
Julia Martino
Purav Vagadia

Publication Date

January 2011

Abstract

A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

Disciplines

Organic Chemistry

Recommended Citation

Mohan, Ram; Bockman, Matthew; Angeles, Veronica; Martino, Julia; and Vagadia, Purav, "A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate" (2011). Scholarship. 9.
https://digitalcommons.iwu.edu/chem_scholarship/9