Bismuth(III) bromide catalyzed Michael addition of allyltrimethylsilanes to α,β-unsaturated ketones
Submission Type
Event
Faculty Advisor
Ram S. Mohan
Expected Graduation Date
2021
Location
Center for Natural Sciences, Illinois Wesleyan University
Start Date
4-13-2019 2:00 PM
End Date
4-13-2019 3:00 PM
Disciplines
Education
Abstract
The products of 1,4-addition of nucleophiles to α,β-unsaturated ketones are of interest as they are easily amenable to further synthetic manipulations. We have studied the utility of bismuth bromide and other Lewis acid catalysts for the conjugate addition of allyltrimethylsilanes to α,β-unsaturated ketones. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.
Bismuth(III) bromide catalyzed Michael addition of allyltrimethylsilanes to α,β-unsaturated ketones
Center for Natural Sciences, Illinois Wesleyan University
The products of 1,4-addition of nucleophiles to α,β-unsaturated ketones are of interest as they are easily amenable to further synthetic manipulations. We have studied the utility of bismuth bromide and other Lewis acid catalysts for the conjugate addition of allyltrimethylsilanes to α,β-unsaturated ketones. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.