Bismuth(III) triflate catalyzed synthesis of substituted hexahydroimidazo[1, 2-a]pyridines
Submission Type
Event
Faculty Advisor
Ram Mohan
Expected Graduation Date
2020
Location
Center for Natural Sciences, Illinois Wesleyan University
Start Date
4-13-2019 2:00 PM
End Date
4-13-2019 3:00 PM
Disciplines
Education
Abstract
The synthesis of nitrogen containing heterocycles is of particular interest in the pharmaceutical industry due to the numerous biological activities exhibited by such compounds. Their synthesis using multicomponent reactions saves steps, and minimizes waste generation. We have investigated the utility of bismuth(III) triflate as a catalyst for the multicomponent synthesis of a series of hexahydroimidazo[1, 2-a]pyridines. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.
Bismuth(III) triflate catalyzed synthesis of substituted hexahydroimidazo[1, 2-a]pyridines
Center for Natural Sciences, Illinois Wesleyan University
The synthesis of nitrogen containing heterocycles is of particular interest in the pharmaceutical industry due to the numerous biological activities exhibited by such compounds. Their synthesis using multicomponent reactions saves steps, and minimizes waste generation. We have investigated the utility of bismuth(III) triflate as a catalyst for the multicomponent synthesis of a series of hexahydroimidazo[1, 2-a]pyridines. Bismuth(III) compounds are especially attractive from a green chemistry perspective because they are remarkably nontoxic, non-corrosive and relatively inexpensive. The results of this study will be presented.