The Effect of Chronic Stress on Stroke Rehabilitation
Submission Type
Event
Faculty Advisor
Abigail Kerr
Expected Graduation Date
2020
Location
Center for Natural Sciences
Start Date
4-4-2020 2:00 PM
End Date
4-4-2020 3:00 PM
Disciplines
Education | Neuroscience and Neurobiology
Abstract
Ischemic stroke is a prominent global health issue and is the 5th leading cause of death worldwide. There are many common risk factors for stroke, including chronic stress. Chronic stress causes a disruption in the physiological homeostasis of the individual, and specifically the homeostasis of the limbic system. In stroke rehabilitation, the limbic system is necessary in promoting a successful functional outcome, and a disruption of this integral system could possibly lead to a worsened functional outcome. While chronic stress has not been thoroughly investigated in the context of stroke rehabilitation and recovery, experimentation and analyses have investigated both the molecular sequelae and behavioral data that coincide with each condition individually. The current study aims to establish if chronic stress compounded with ischemic stroke has an effect on post-rehabilitative functional outcome using a novel behavioral study with the mouse as a model organism.
The Effect of Chronic Stress on Stroke Rehabilitation
Center for Natural Sciences
Ischemic stroke is a prominent global health issue and is the 5th leading cause of death worldwide. There are many common risk factors for stroke, including chronic stress. Chronic stress causes a disruption in the physiological homeostasis of the individual, and specifically the homeostasis of the limbic system. In stroke rehabilitation, the limbic system is necessary in promoting a successful functional outcome, and a disruption of this integral system could possibly lead to a worsened functional outcome. While chronic stress has not been thoroughly investigated in the context of stroke rehabilitation and recovery, experimentation and analyses have investigated both the molecular sequelae and behavioral data that coincide with each condition individually. The current study aims to establish if chronic stress compounded with ischemic stroke has an effect on post-rehabilitative functional outcome using a novel behavioral study with the mouse as a model organism.