The Effect of Chronic Stress on Stroke Rehabilitation

Presenter and Advisor Information

Alexander H. Palacios, Illinois Wesleyan University

Submission Type

Event

Faculty Advisor

Abigail Kerr

Expected Graduation Date

2020

Location

Center for Natural Sciences

Start Date

4-4-2020 2:00 PM

End Date

4-4-2020 3:00 PM

Disciplines

Education | Neuroscience and Neurobiology

Abstract

Ischemic stroke is a prominent global health issue and is the 5th leading cause of death worldwide. There are many common risk factors for stroke, including chronic stress. Chronic stress causes a disruption in the physiological homeostasis of the individual, and specifically the homeostasis of the limbic system. In stroke rehabilitation, the limbic system is necessary in promoting a successful functional outcome, and a disruption of this integral system could possibly lead to a worsened functional outcome. While chronic stress has not been thoroughly investigated in the context of stroke rehabilitation and recovery, experimentation and analyses have investigated both the molecular sequelae and behavioral data that coincide with each condition individually. The current study aims to establish if chronic stress compounded with ischemic stroke has an effect on post-rehabilitative functional outcome using a novel behavioral study with the mouse as a model organism.

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Apr 4th, 2:00 PM Apr 4th, 3:00 PM

The Effect of Chronic Stress on Stroke Rehabilitation

Center for Natural Sciences

Ischemic stroke is a prominent global health issue and is the 5th leading cause of death worldwide. There are many common risk factors for stroke, including chronic stress. Chronic stress causes a disruption in the physiological homeostasis of the individual, and specifically the homeostasis of the limbic system. In stroke rehabilitation, the limbic system is necessary in promoting a successful functional outcome, and a disruption of this integral system could possibly lead to a worsened functional outcome. While chronic stress has not been thoroughly investigated in the context of stroke rehabilitation and recovery, experimentation and analyses have investigated both the molecular sequelae and behavioral data that coincide with each condition individually. The current study aims to establish if chronic stress compounded with ischemic stroke has an effect on post-rehabilitative functional outcome using a novel behavioral study with the mouse as a model organism.