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In 2018, nearly 57% of American adults reported drinking alcohol in the past month, and 41.5% of current drinkers reported taking alcohol-interactive (AI) medications. Consuming alcohol and medications concurrently may result in adverse effects. The purpose of this study was to determine the effectiveness of a one-hour lecture about AI medications in a class of undergraduate nursing students (N = 48) at a small Midwestern university. The Jarvis Nursing Knowledge of Alcohol-Interactive Medications survey was distributed on August 27, 2018, and again on November 19, 2018. A significant increase was found between pretest and posttest on correct identification of mechanism (27.47 ± 14.18 vs. 37.33 ± 16.60; t =3.15; p < .02). A significant increase was also found between pretest and posttest scores on the ability to discriminate a medication as AI or Non-AI (68.5% ± 6.3 vs 71.5% ± 6.5; t= 2.5; p <. 02). While scores increased significantly, students failed to consistently recognize the correct medication-alcohol interaction. A one-hour lecture emphasizing AI medications in the pre-licensure program enhanced students’ knowledge; however, future research is needed to determine retention of AI medication knowledge.



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